Physical activity makes the brain cells grow and protects against Alzheimer’s

Through Sport, which is set against Alzheimer’s protective hormone Irisin free

Can Sport and physical activity protect people from the onset of Alzheimer’s? Researchers noted now that physical activity triggers a hormone, which can contribute to the Regrowth of brain cells. This seems to lead to an improved protection against Alzheimer’s.

The scientists from the Columbia University found in their recent study, exercise reduced people’s risk for the onset of Alzheimer’s disease by a released hormone, called Irisin, before memory loss and brain damage. The doctors published the results of their study in the English journal “Nature Medicine”.

Sports protects the brain

A new series of studies has shown that while the athletic training released a hormone (Irisin) Alzheimer’s patients and animals from memory loss and brain damage. In experiments on mice, the experts noticed that the animals did not develop any memory problems, although they were infused with Beta-Amyloid (the in the development of Alzheimer’s involved in Protein that leads to accumulation of deposits in the brain). The reason for this could be the physical activity of the mice. The animals swam for a period of five weeks almost every, experts say.

People should do more sports

This finding suggests that exercise and activity can actually protect against the development of dementia, in addition, the drug, Irisin seems to be a potential for prevention of the disease, explain the doctors. The results should encourage people to be more active, this would support your brain function and overall health, adds the study’s author, Professor Dr. Ottavio Arancio of Columbia University. Exercise, unfortunately, is not for all people, especially for people with age-related diseases such as heart disease, Arthritis, or dementia. Just for these people, a special demand for drugs, which can mimic the effects of Irisin, synapses, protect, and cognitive decline prevent, the expert says. Despite decades of research and many studies, it has been found so far, no drug, Alzheimer’s, reverses, or prevents.

Irisin stimulates the growth of brain cells in the Hippocampus

The hormone Irisin stimulates the growth of brain cells in the Hippocampus, a Region of the brain associated with memory and Learning. Only two areas of the brain in adulthood, brain cells grow back, the Hippocampus is one of the first areas to deteriorate in people with Alzheimer’s. Irisin could explain, contribute to, and why physical activity improves memory and brain diseases such as Alzheimer’s disease seems to play a protective role, explains Professor Dr. Arancio.

People with Alzheimer’s have lower iris inspiegel

On the basis of tissue samples from brain banks the researchers found that in the human Hippocampus, Irisin is present and that the hormone levels are in the Hippocampus in people with Alzheimer’s low. Animal studies dealing with the effects of Irisin on the brain, found that it protects the brain synapses and memory. As Irisin in the Hippocampus of healthy mice has been disabled, have been weakened synapses and memory. The increase of the concentration of Irisin in the brain, improved synapses, and memory.

Further research is needed

The Blockade of Irisin with a drug eliminated the benefits of swimming for the memory of the mice completely, say the researchers. Mice were treated and swam with Irisin blocking agents, showed in the case of memory tests, no better results than the sedentary animals, if the animals infusions with Beta-Amyloid were administered. The scientists are now looking for active pharmaceutical ingredients, which can increase the hormone in the brain, or the effect of mimic. (as)